25 – Luoyang is declared capital of the Eastern Han dynasty by Emperor Guangwu of Han.
176 – Emperor Marcus Aurelius grants his son Commodus the rank of "Imperator" and makes him Supreme Commander of the Roman legions.
395 – Rufinus, praetorian prefect of the East, is murdered by Gothic mercenaries under Gainas.
511 – King Clovis I dies at Paris ("Lutetia") and is buried in the Abbey of St Genevieve. The Merovingian dynasty is continued by his four sons, Theuderic I, Chlodomer, Childebert I and Chlothar I, who divide the Frankish Kingdom and rule from the capitals at Metz, Orléans, Paris and Soissons.
602 – Emperor Maurice is forced to watch his five sons be executed before being beheaded himself; their bodies are thrown into the sea and their heads are exhibited in Constantinople.
1095 – Pope Urban II declares the First Crusade at the Council of Clermont.
1703 – The first Eddystone Lighthouse is destroyed in the Great Storm of 1703.
1727 – The foundation stone to the Jerusalem Church in Berlin is laid.
1807 – The Portuguese Royal Family leaves Lisbon to escape from Napoleonic troops.
1810 – The Berners Street hoax was perpetrated by Theodore Hook in the City of Westminster, London.
1815 – Adoption of Constitution of the Kingdom of Poland.
1830 – Saint Catherine Labouré experiences a vision of the Blessed Virgin standing on a globe, crushing a serpent with her feet, and emanating rays of light from her hands.
1835 – James Pratt and John Smith are hanged in London; they are the last two to be executed for sodomy in England.
1839 – In Boston, Massachusetts, the American Statistical Association is founded.
1856 – The Coup of 1856 leads to Luxembourg's unilateral adoption of a new, reactionary constitution.
1863 – American Civil War: Confederate cavalry leader John Hunt Morgan and several of his men escape the Ohio Penitentiary and return safely to the South.
1863 – American Civil War: Battle of Mine Run: Union forces under General George Meade take up positions against troops led by Confederate General Robert E. Lee.
1868 – American Indian Wars: Battle of Washita River: United States Army Lieutenant Colonel George Armstrong Custer leads an attack on Cheyenne living on reservation land.
1886 – German judge Emil Hartwich sustains fatal injuries in a duel, which would become the background for Theodor Fontane's Effi Briest.
1895 – At the Swedish–Norwegian Club in Paris, Alfred Nobel signs his last will and testament, setting aside his estate to establish the Nobel Prize after he dies.
1896 – Also sprach Zarathoustra by Richard Strauss is first performed.
1901 – The U.S. Army War College is established.
1912 – Spain declares a protectorate over the north shore of Morocco.
1924 – In New York City, the first Macy's Thanksgiving Day Parade is held.
1940 – In Romania, the ruling Iron Guard fascist party assassinates over 60 of arrested King Carol II of Romania's aides and other political dissidents, including former Prime Minister Nicolae Iorga.
1940 – World War II: At the Battle of Cape Spartivento, the Royal Navy engages the Regia Marina in the Mediterranean Sea.
1942 – World War II: At Toulon, the French navy scuttles its ships and submarines to keep them out of Nazi hands.
1944 – World War II: RAF Fauld explosion: An explosion at a Royal Air Force ammunition dump in Staffordshire kills seventy people.
1945 – CARE (then the Cooperative for American Remittances to Europe) was founded to a send CARE Packages of food relief to Europe after World War II.
1954 – Alger Hiss is released from prison after serving 44 months for perjury.
1963 – The Convention on the Unification of Certain Points of Substantive Law on Patents for Invention is signed at Strasbourg.
1965 – Vietnam War: The Pentagon tells U.S. President Lyndon B. Johnson that if planned operations are to succeed, the number of American troops in Vietnam has to be increased from 120,000 to 400,000.
1968 – Penny Ann Early became the first woman to play major professional basketball, for the Kentucky Colonels in an ABA game against the Los Angeles Stars.
1971 – The Soviet space program's Mars 2 orbiter releases a descent module. It malfunctions and crashes, but it is the first man-made object to reach the surface of Mars.
1973 – Twenty-fifth Amendment: The United States Senate votes 92–3 to confirm Gerald Ford as Vice President of the United States. (On December 6, the House will confirm him 387–35).
1975 – The Provisional IRA assassinates Ross McWhirter, after a press conference in which McWhirter had announced a reward for the capture of those responsible for multiple bombings and shootings across England.
1978 – In San Francisco, city mayor George Moscone and openly gay city supervisor Harvey Milk are assassinated by former supervisor Dan White.
1978 – The Kurdistan Workers' Party (PKK) is founded in the city of Riha (Urfa) in Turkey.
1983 – Avianca Flight 011: A Boeing 747 crashes near Madrid's Barajas Airport, killing 181.
1984 – Under the Brussels Agreement signed between the governments of the United Kingdom and Spain, the former agreed to enter into discussions with Spain over Gibraltar, including sovereignty.
1987 – On a routine flight between Taiwan and Mauritius, South African Airways Flight 295 experiences an in-flight fire, apparently starting at around 23:48 on the 27th. After just under 16 minutes (leading into the early hours of November 28), the plane crashes and kills all 159 on board.
1989 – Avianca Flight 203: A Boeing 727 explodes in mid-air over Colombia, killing all 107 people on board and three people on the ground. The Medellín Cartel will claim responsibility for the attack.
1991 – The United Nations Security Council adopts Security Council Resolution 721, leading the way to the establishment of peacekeeping operations in Yugoslavia.
1992 – For the second time in a year, military forces try to overthrow president Carlos Andrés Pérez in Venezuela.
1997 – Twenty-five are killed in the second Souhane massacre in Algeria.
1999 – The left-wing Labour Party takes control of the New Zealand government with leader Helen Clark becoming the first elected female Prime Minister in New Zealand's history.
2001 – A hydrogen atmosphere is discovered on the extrasolar planet Osiris by the Hubble Space Telescope, the first atmosphere detected on an extrasolar planet.
2004 – Pope John Paul II returns the relics of Saint John Chrysostom to the Eastern Orthodox Church.
2006 – The Canadian House of Commons approves a motion tabled by Prime Minister Stephen Harper recognizing the Québécois as a nation within Canada.
2009 – Nevsky Express bombing: A bomb explodes on the Nevsky Express train between Moscow and Saint Petersburg, derailing it and causing 28 deaths and 96 injuries.
2015 – An active shooter inside a Planned Parenthood facility in Colorado Springs, Colorado, USA, shoots at least four members of the Colorado Springs Police Department. One officer later dies. Two civilians were also killed, and six injured. The shooter later surrendered.